A groundbreaking treatment for complex vascular malformations, which mainly affect children and teenagers, has been performed for the first time in Israel at the angiography unit of Shaare Zedek Medical Center in Jerusalem. The method uses short, controlled electrical pulses to significantly improve the penetration of medication into the abnormal cells and eliminate the need for long series of repeated invasive procedures.<\/p>\n\n\n\n
Vascular malformations are a diverse group of disorders affecting the blood vessel system. They may cause pain, swelling, bleeding and impaired physical function. Some cases are especially complex and do not respond adequately to conventional treatment, leaving young patients to undergo repeated procedures over many years in an effort to control their symptoms.<\/p>\n\n\n\n
The standard treatment in Israel and around the world has generally involved injecting medication directly into the malformation in a procedure known as sclerotherapy. The purpose of the injection is to shrink the abnormal blood vessels and reduce pain and other symptoms.<\/p>\n\n\n\n
In some cases, however, the treatment has only a limited or temporary effect. Patients may therefore be required to undergo repeated catheterizations and injections, sometimes without achieving sufficient improvement. The technology introduced at Shaare Zedek is intended to provide an answer even for severe cases that failed to respond to previous treatments.<\/p>\n\n\n\n
During the procedure, the medical team delivers the drug bleomycin into the malformation through a tiny catheter. A special probe then sends a short and carefully controlled electrical pulse to the treated area.<\/p>\n\n\n\n
The pulse temporarily and reversibly opens tiny pores in the cell membranes, allowing the medication to enter the cells at a concentration that Shaare Zedek says is up to 10,000 times higher than with conventional treatment. The process enables the team to target the malformation more effectively while dramatically reducing the number of procedures required.<\/p>\n\n\n\n
Dr. Adam Farkas, director of the angiography unit at Shaare Zedek and the physician leading the new treatment, noted: “We are seeing fantastic results in practice, especially among young patients who had already undergone multiple invasive treatments at other hospitals without success. This innovative treatment is finally providing a real and rapid solution to their condition.”<\/p>\n\n\n\n
According to Dr. Farkas, the results have led the hospital to refer most patients arriving with vascular malformations directly to the reversible electroporation pathway. Last week, specialists from hospitals across Israel visited the unit to observe the procedures and learn from the experience accumulated in Jerusalem.<\/p>\n\n\n\n
The experts also took part in an international webinar led by Professor Walter Wohlgemuth of Germany, one of the pioneers and developers of the method, as part of efforts to expand the use of the technology to additional medical centers.<\/p>\n","protected":false},"excerpt":{"rendered":"
A groundbreaking treatment for complex vascular malformations, which mainly affect children and teenagers, has been performed for the first time in Israel at the angiography unit of Shaare Zedek Medical Center in Jerusalem. The method uses short, controlled electrical pulses to significantly improve the penetration of medication into the abnormal cells and eliminate the need […]<\/p>\n","protected":false},"author":7,"featured_media":182662,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_robots_follow":"","_seopress_robots_imageindex":"","_seopress_robots_snippet":"","_seopress_robots_primary_cat":"10421","_seopress_robots_breadcrumbs":"","_seopress_robots_freeze_modified_date":"","_seopress_robots_custom_modified_date":"","_seopress_robots_canonical":"","_seopress_social_fb_title":"","_seopress_social_fb_desc":"","_seopress_social_fb_img":"","_seopress_social_fb_img_attachment_id":0,"_seopress_social_fb_img_width":0,"_seopress_social_fb_img_height":0,"_seopress_social_twitter_title":"","_seopress_social_twitter_desc":"","_seopress_social_twitter_img":"","_seopress_social_twitter_img_attachment_id":0,"_seopress_social_twitter_img_width":0,"_seopress_social_twitter_img_height":0,"_seopress_redirections_value":"","_seopress_redirections_enabled":"","_seopress_redirections_enabled_regex":"","_seopress_redirections_logged_status":"","_seopress_redirections_param":"","_seopress_redirections_type":0,"_seopress_analysis_target_kw":"","footnotes":""},"categories":[62,74,8730,68],"tags":[],"class_list":["post-182664","post","type-post","status-publish","format-standard","has-post-thumbnail","category-breaking","category-health","category-8730","category-68"],"acf":{"subtitle":"Technology introduced for the first time in Israel at Shaare Zedek Hospital in Jerusalem dramatically increases drug penetration into complex vascular malformations"},"_links":{"self":[{"href":"https:\/\/jerusalem-online.co.il\/en\/wp-json\/wp\/v2\/posts\/182664","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jerusalem-online.co.il\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jerusalem-online.co.il\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jerusalem-online.co.il\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/jerusalem-online.co.il\/en\/wp-json\/wp\/v2\/comments?post=182664"}],"version-history":[{"count":2,"href":"https:\/\/jerusalem-online.co.il\/en\/wp-json\/wp\/v2\/posts\/182664\/revisions"}],"predecessor-version":[{"id":182671,"href":"https:\/\/jerusalem-online.co.il\/en\/wp-json\/wp\/v2\/posts\/182664\/revisions\/182671"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/jerusalem-online.co.il\/en\/wp-json\/wp\/v2\/media\/182662"}],"wp:attachment":[{"href":"https:\/\/jerusalem-online.co.il\/en\/wp-json\/wp\/v2\/media?parent=182664"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jerusalem-online.co.il\/en\/wp-json\/wp\/v2\/categories?post=182664"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jerusalem-online.co.il\/en\/wp-json\/wp\/v2\/tags?post=182664"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}